Anti-Emetics

Dimenhydrinate (Dramamine)

• 50mg PO/IM/IV q4h
• indicated for N/V associated with motion sickness

 

Dronabinol (Marinol)

• 2.5mg PO bid before lunch and dinner
• Indicated for N/V associated with chemotherapy

 

Granisetron (Kytril)

• 10 mcg/kg IV 30 min before chemo, 1mg PO bid
• indicated for N/V associated with chemotherapy

 

Ondansetron (Zofran)

• single 32mg (infused over 15 minutes)
• three 0.15 mg/kg IV doses
• 8-10mg PO bid [4, 8, solution 4mg/5ml]
• indicated for N/V associated with chemotherapy

 

Prochlorperazine (Compazine)

• 5-10mg PO/IM tid/qid
• 2.5-10mg slow (5mg/min) IV - single dose not to exceed 10mg
• supp 25mg bid
• maximum daily dose 40mg
• also effective for short term treatment of non-psychotic anxiety

 

Promethazine (Phenergan)

• 25-50mg PO/IM/PR q4-6h
• Peds 0.25 - 0.5mg/kg PO/IM/PR q4-6h
• indicated for
  • post-op N/V associated with anesthesia
  • motion sickness
  • adjuct to analgesics for control of post-op pain (potentiates Demerol)
  • effective for allergic conditions

 

Scopolamine (TransdermScop)

• one circular patch applied to the postauricular area
• takes 4 hrs to become effective and lasts for 3 days
• indicated for N/V associated with motion sickness
• wash hands after handing - causes dilation of pupils and blurred vision if comes in contact with the eyes

 

Thiethylperazine (Torecan, Norzine)

• 10-30mg qd-tid
• 2ml IM qd-tid

 

Trimethobenzamide (Tigan)

• 250mg PO tid/qid
• Peds 100mg PO tid/qid
• Supp 200mg tid/qid - Peds 100mg tid/qid